Our lab studies how sex hormones modulate brain function, particularly in the context of declining sex hormones, such as aging and menopause.
Are there sex differences in the trajectories of age-related cognitive decline ?
Can we identify predictors of pathological aging?
Menopausal women complain of 3 major symptoms: cognitive deficits, sleep disturbances and hot flashes.
All are triggered by estrogen loss, but we know very little about the mechanisms
Emily Rothwell awarded a postdoctoral NIH F32 award!
Check out new papers by lab members !
Vaughan E, Le A, Casey M, Workman K & Lacreuse, A (in press). Baseline cortisol levels and social behavior differ as a function of handedness in marmosets (Callithrix jacchus). American Journal of Primatology.
LaClair M, Febo M, Nephew B, Gervais NJ, Poirier G, Workman K, Chumachenko S, Payne L, Moore MC, King JA & Lacreuse, A. (2019). Sex differences in cognitive flexibility and resting brain networks in middle-aged marmosets. eneuro:ENEURO.0154-19.2019.
related media https://blogs.umass.edu/ions/2019/07/02/sexdifferencesmarmosets/
Gervais, N. J., Remage-Healey, L., Starrett, J. R., Pollak, D. J., Mong, J. A., & Lacreuse, A. (2018). Adverse effects of aromatase inhibition on the brain and behavior in a non-human primate. J Neurosci. doi: 10.1523/jneurosci.0353-18.2018
Workman, K. P., Healey, B., Carlotto, A., & Lacreuse, A. (2018). One‐year change in cognitive flexibility and fine motor function in middle‐aged male and female marmosets (Callithrix jacchus). American journal of primatology, e22924.
